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List of pandemics

Epidemics/pandemicsDiseaseVirus/BacteriumDeath tollGlobal population lostRegional population lostDateLocation
Black deathBubonic plagueBacterium - Yersinia pestis75-200 million17-54%30-60% european population1346-1353Europe, Asia, and North Africa
Spanish fluInfluenza A/H1N1Influenza virus A/H1N117-100 million1-5.4%-1918-1920Worldwide
Plague of JustinianBubonic plagueBacterium - Yersinia pestis15-100 million7-56%25-60 % european population541-549Europe and West Asia
HIV/AIDS global pandemicHIV/AIDSvirus HIV36.3 million1981-presentWorldwide
Third plague pandemicBubonic plagueBacterium - Yersinia pestis12-15 million1855-1960Worldwide
COVID-19 pandemicCOVID-19virus SARS-CoV-25.6-22 million0.07-0.27%2019-presentWorldwide
Cocoliztli epidemicCocoliztlibacterium - Salmonella enterica - Paratyphi C5-15 million1-3%27-80% of Mexican population1545-1548Mexico
Antonine PlagueSmallpox or measlesvariola major/minor (VARV) or measles morbillivirus (MeV)5-10 million3-6%25-33% of Roman population165-180Roman empire
1520 Mexico smallpox epidemicSmallpoxvariola major/minor (VARV)5-8 million1-2%23-37% of Mexican population1519-1520Mexico
1918-1922 Russia typhus epidemicTyphusbacteria: Rickettsia prowazekii, Orientia tsutsugamushi and Rickettsia typhi2-3 million0.1-0.16%1-1.6% of Russian population1918-1922Russia
1957-1958 influenza pandemicInfluenza A/H2N2A/H2N2 virus1-4 million0.03-0.1%1957-1958Worldwide
Hong Kong fluInfluenza A/H3N2A/H3N2 virus1-4 million0.03-0.1%1968-1969Worldwide
Cocoliztli epidemic of 1576Cocoliztlibacterium - Salmonella enterica - Paratyphi C2-2.5 million0.4-0.5%50% of Mexican population1576-1580Mexico
735-737 Japanese smallpox epidemicSmallpoxvariola major/minor (VARV)2 million1%33% of Japanese population735-737Japan
1772-1773 Persian PlagueBubonic plagueBacterium - Yersinia pestis2 million0.2-0.3%1772-1773
Naples PlagueBubonic plagueBacterium - Yersinia pestis1.25 million0.2%1656-1658Southern Italy
1846-1860 cholera pandemicCholerabacterium Vibrio cholerae1 million0.08%1846-1860Worldwide
1629-1631 Italian plagueBubonic plagueBacterium - Yersinia pestis1 million0.2%1629-1631Italy
1889-1890 flu pandemicInfluenza or coronavirus diseasevirus A/H3N8, A/H2N2, or coronavirus OC431 million0.07%1889-1890Worldwide

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